Product Category
Products > Biolab Use EnzymesPenase, Penicillinase
Name:Penase, Penicillinase
Description:
 

Description

        Penase (full name Penicillinase, also named β-lactamase type I,EC 3.5.2.6),can hydrolyze β- lactam antibiotic β-lactam ring, which makes it loses its anti-microbial activity. This product is a recombinant enzyme obtained by genetic engineering technology. Through the construction of a highly efficient expression E.coli strain of penicillinase and fermentation, purification, a high purity and high activity product is obtained. Penase is characterized by strong specificity and effectively hydrolyze β-Lactam antibiotics such as penicillin G, ampicillin, ampicillin, amoxicillin, piramicillin, carbenicillin, ticarcillin, furbenicillin, mezlocillin, etc.

Appearance

        Colorless or pain yellow clear liquid.

Package

        5ml/bottle   100ml/bottle

Specifications

        Activity:      ≥10 MU/ml
        Purity:         > 95 % by SDS-PAGE
        Sterility:      Negtive
        pH:              6.0~8.0
 
Unit definition

        One unit is defined as the amount of enzyme required to hydrolyze one biological unit of penicillin G in one hour at pH 7.0, 37˚C.

Application

        Environmental monitoring of antibiotic manufacturing areas; 

       Sterility testing of bulk Antibiotics;

        Testing sterility of blood cultures;

        Testing for β-lactam contamination of drugs.

Stability

       Stable at 2~8℃for more than two years since report.

Catalog #

      DU-12-1005